I winterized my boat before winter storage for the first time and I took pictures and noted the steps. The motor is a 140HP Suzuki 4-Stroke. I stopped into a local boat dealer to pick up the materials and get some direction. The steps are listed below.
Materials:
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Gas treatment
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Oil (4 stroke synthetic blend)
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Lower unit grease
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Oil filter
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Water hose & motor ear muffs (if needed....most new motors have a built-in hose connector)
Step #1:
Hook up ear muffs to motor and turn on water

Step #2
Add the gas treatment to the a gallon of gas in a seperate can.

Step #3
Start the motor and let the treatment run through until the motor quits. Took around 20 minutes. Turn off water.
Step #4
Drain motor oil from side casing

Step #5
Remove oil filter

Step #6
Replace filter and add new oil

Step #7
Drain lower unit grease

Step #8
Use lower unit grease pump to pump in new lower unit grease

Step #9
Remove cotter pin from prop shaft and remove prop to grease the prop shaft

Step #10
Last thing.....grease the wheels of your trailer 

Not bad for my first time doing it. It took a bit of time to find some of the screws on the motor to remove to get to the oil filter and some other things took a bit to figure out, but now that I have done it once, it should be a breeze next time. Should be able to cut if from a couple hours to no longer than an hour next time.